Quick Verdict
Revolution Plus is the broadest-coverage topical cat parasite treatment available. One monthly application covers fleas, ticks, ear mites, roundworm, hookworm, and heartworm. The $75-95 price at Canada Pet Care for a 6-pack is 30-40% below US vet clinic pricing for the same product.
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Quick Answers
- Revolution Plus covers fleas, ticks, ear mites, roundworm, hookworm, and heartworm
- Apply monthly to the back of the neck β no oral dosing needed
- Contains selamectin + sarolaner β different mechanism from dog isoxazolines
- Price at Canada Pet Care: $75-95 for a 6-pack vs $110-140 at US vet clinics
- Safe for cats 8 weeks and older, minimum 2.8 lbs
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What Revolution Plus actually covers
Revolution Plus (selamectin + sarolaner) is a monthly topical applied to the back of a cat's neck. One application covers six parasites β for full pricing and alternatives, see our Canada Pet Care review:
- Fleas (Ctenocephalides felis) β kills adults and prevents egg development
- Ticks β black-legged tick, Gulf Coast tick, American dog tick
- Ear mites (Otodectes cynotis)
- Heartworm disease (Dirofilaria immitis) β prevention, not treatment
- Roundworm (Toxocara cati)
- Hookworm (Ancylostoma tubaeforme)
The original Revolution (selamectin only) covered the same parasites minus ticks. Revolution Plus added sarolaner specifically to add tick coverage to an already-established product.
How it works
Selamectin absorbs through the skin into the bloodstream and then into skin secretions. It targets glutamate-gated chloride channels in parasites, paralyzing and killing them. It reaches ear mites through contact and systemic circulation; it kills heartworm larvae before they mature.
Sarolaner (the same active ingredient as in Simparica for dogs, formulated for cats) is the isoxazoline component that covers ticks and strengthens flea efficacy.
How to apply it
Part the fur at the base of the skull to expose skin. Press the applicator tip against the skin and empty the full tube in one spot. Let dry for 2 hours before the cat gets wet or is handled extensively by children.
Do not apply to broken skin. Do not apply to cats that are ill or underweight. The most common application error is applying to fur instead of skin β the product needs direct skin contact to absorb properly.
Revolution Plus vs original Revolution
If your cat lives indoors and has no tick exposure, the original Revolution covers everything except ticks. The tick coverage in Revolution Plus is only relevant if your cat goes outside or is in an area with tick exposure. For indoor-only cats with no tick risk, original Revolution at a lower price is a reasonable choice.
For cats with any outdoor access β even a screened porch β Revolution Plus is the better call. Ticks can travel in on clothing and other pets.
Cost at Canada Pet Care vs US vets
US vet clinic pricing for Revolution Plus runs $110-140 for a 6-pack. Canada Pet Care sources the same Zoetis-manufactured product from licensed international pharmacies and prices it at $75-95 for a 6-pack β a saving of $35-65 per 6 months. Free shipping on orders over $49, ships to all 50 states.
Frequently asked questions
Can Revolution Plus be used on kittens?
Approved for kittens 8 weeks and older, minimum weight 2.8 lbs. Do not use on kittens under 8 weeks β they lack the liver enzymes needed to metabolize sarolaner safely.
Is Revolution Plus safe for pregnant cats?
Not evaluated in pregnant, nursing, or breeding cats. Consult your vet before using on cats in any of these categories.
What if my cat grooms the application site?
Apply to the base of the skull where the cat cannot reach to groom. If a cat does ingest some of the product, salivation and vomiting can occur. This is not dangerous in small amounts but apply to the correct location to avoid it.
Will Revolution Plus treat an existing ear mite infestation?
Yes. A single application is effective against ear mites. However, debris should be gently cleaned from the ear canal before application to allow the medication to work effectively.
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Pros & Cons
Pros
- Six-parasite coverage in one monthly application
- No oral dosing β easier for cats that resist pills
- $35-65 cheaper per 6 months at Canada Pet Care vs US vets
- Covers heartworm β often overlooked in cats
- Established selamectin base with added sarolaner for ticks
Cons
- Prescription required in US (available without Rx at Canada Pet Care)
- Keep dry for 2 hours post-application
- Not for kittens under 8 weeks or under 2.8 lbs
- Indoor-only cats may not need tick coverage
Comparison Table
| Product | Fleas | Ticks | Ear Mites | Heartworm | Roundworm/Hookworm | Price/6mo at CPC |
|---|---|---|---|---|---|---|
| Revolution Plus | Yes | Yes | Yes | Yes | Yes | $75-95 |
| Revolution (original) | Yes | No | Yes | Yes | Yes | $55-70 |
| Frontline Plus (cat) | Yes | Yes | No | No | No | $40-55 |
| Bravecto (cat) | Yes | Yes | Yes | No | No | $55-65 |
Bottom Line
Six-parasite coverage in one topical application is genuinely convenient for cat owners. Revolution Plus is the only product in this tier that covers all six. Canada Pet Care's pricing ($75-95 for a 6-pack) makes a strong case for it vs buying multiple single-parasite products.