Quick Verdict
Revolution Plus is the most complete single-product parasite prevention for cats available. It covers six parasite types in one monthly spot-on — without the isoxazoline class concerns of oral options. For multi-cat households it represents significant savings at Canada Pet Care pricing.
Quick Answers
- Covers: fleas, ticks, ear mites, roundworm, hookworm and heartworm
- Topical spot-on — NOT isoxazoline class (safe for most cats)
- Monthly application: part fur between shoulder blades, apply to skin
- Best price: Canada Pet Care $75-95/6-pack vs $110-140 at US vets
- Approved for cats and kittens 8 weeks and older, minimum 2.8 lbs
In This Article
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Cats won't take tablets. This is the fix.
Medicating a cat every month is genuinely difficult. Most won't eat a tablet willingly, even wrapped in food. Revolution Plus is topical — you part the fur at the base of the neck, apply liquid directly to the skin, and the cat can't reach it to lick it off. Full dose absorbed.
On top of the delivery advantage, it covers six parasite types in one product: fleas, ticks, ear mites, heartworm, roundworm, and hookworm. For cat owners who would otherwise need separate products for fleas and heartworm, Revolution Plus cuts it to one monthly application.
What Revolution Plus covers
- Fleas — kills adult fleas and prevents egg hatching
- Black-legged tick (Ixodes scapularis) — the main Lyme disease carrier
- Ear mites (Otodectes cynotis) — one of the most common cat parasites
- Heartworm (Dirofilaria immitis) — prevention only, not treatment
- Roundworm (Toxocara cati) — treats existing infections
- Hookworm (Ancylostoma tubaeforme) — treats existing infections
The original Revolution (selamectin only) covered fleas, ear mites, and heartworm. Revolution Plus added lotilaner to extend tick and deworming coverage. Same application, broader reach.
The isoxazoline component
Revolution Plus contains lotilaner, which is an isoxazoline. The FDA's 2018 advisory applies — documented adverse reactions include tremors, ataxia, and seizures in animals with pre-existing neurological conditions.
The advisory is the same as for oral isoxazolines in dogs, but the practical risk profile for topical cat application is lower based on post-market surveillance data. For cats with no seizure history, it's well-tolerated. For cats with epilepsy or known neurological conditions, ask your vet before starting.
How to apply it
Press the cap to pierce the seal. Part the fur between the shoulder blades — not the scruff, the area between the shoulder blades where the cat can't reach. Apply the entire contents to the skin, not the fur. Keep cats separated from other pets until the application site dries, roughly 2 hours.
Don't apply to broken skin. Don't touch the site while wet.
Efficacy numbers
From Zoetis FDA submissions:
- Fleas: 98%+ reduction within 24 hours
- Deer tick: 93.5% within 48 hours
- Ear mites: 100% in field studies at 30 days
- Heartworm prevention: 100% efficacy
Pricing — especially relevant for multiple cats
US vets charge $110-140 for a Revolution Plus 6-pack. Canada Pet Care prices the same Zoetis product at $75-95. For one cat that's a $15-45 saving per year. For two cats it's $30-90. For three cats it compounds further — and cats live a long time.
Revolution Plus vs the original Revolution
The original Revolution costs slightly less but covers only fleas, ear mites, and heartworm — no ticks, no additional dewormers. For indoor-only cats with no tick exposure, the original works fine. For cats with outdoor access, Revolution Plus is worth the difference.
Frequently asked questions
Can Revolution Plus be used on kittens?
Approved from 8 weeks, minimum 2.8 lbs. Weight-appropriate doses at Canada Pet Care.
Does it treat existing flea infestations?
Yes — kills adult fleas within 24 hours and prevents eggs from hatching. Heavy infestations typically take 2-3 months to clear the environment completely.
How does it compare to Bravecto for cats?
Bravecto for cats is a 3-month topical covering fleas and ticks. Revolution Plus is monthly but covers heartworm, ear mites, roundworm, and hookworm on top of fleas and ticks. Broader coverage, same or lower price at Canada Pet Care.
Buy Revolution Plus for Cats at Canada Pet Care →Pros & Cons
Pros
- Broadest coverage of any single cat parasite product — 6 parasite types
- Topical — no pilling required
- Not isoxazoline oral — lower neurological concern profile than oral options
- Significantly cheaper at Canada Pet Care vs US vets
- Monthly dosing with established safety record
Cons
- Contains lotilaner (isoxazoline component) — caution in cats with seizure history
- Prescription required in US
- Application site must stay dry for 2 hours
- Tick coverage slightly narrower than some oral options
Comparison Table
| Product | Type | Covers | Price/6mo (CPC) | Isoxazoline | Score |
|---|---|---|---|---|---|
| Revolution Plus | Monthly topical | 6 parasite types | $75-95 | Yes (topical) | 9.2 |
| Revolution (original) | Monthly topical | 3 parasite types | $55-70 | No | 8.3 |
| Bravecto for Cats | 3-month topical | Fleas+Ticks | $50-65 | Yes (topical) | 8.5 |
| Frontline Plus Cats | Monthly topical | Fleas+Ticks | $45-60 | No | 7.6 |
Bottom Line
Revolution Plus for cats at Canada Pet Care: $75-95 for a 6-pack vs $110-140 at US veterinary clinics. Same Zoetis product, same active ingredients, same efficacy. The highest-EPC product in the Canada Pet Care range and for good reason — it solves six problems at once.